The Phospho-PARP1 (S782) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PARP-1, PARP1, and PPOL. This antibody recognizes Human, Mouse, Rat, and Hamster antigen. The Phospho-PARP1 (S782) Antibody has been validated for the following applications: Dot Blot, and ELISA.
Description
This gene encodes a chromatin-associated enzyme,
poly(ADP-ribosyl)transferase, which modifies various nuclear
proteins by poly(ADP-ribosyl)ation. The modification is dependent
on DNA and is involved in the regulation of various important
cellular processes such as differentiation, proliferation, and
tumor transformation and also in the regulation of the molecular
events involved in the recovery of cell from DNA damage. In
addition, this enzyme may be the site of mutation in Fanconi
anemia, and may participate in the pathophysiology of type I
diabetes